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Dutas (Dutasteride)

Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal mediator that plays a role in the development and enlargement of the prostate gland. Dutas was approved by the FDA in 2001 for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men as monotherapy or in combination with the α-adrenergic antagonist tamsulosin to enhance the therapeutic response. Its clinical efficacy against benign prostate hyperplasia in male patients is comparable to that of finasteride, a specific type II 5α-reductase inhibitor. However, unlike finasteride, Dutas is not yet indicated for the treatment of androgenic alopecia although it was demonstrated to be effective in several randomized, double-blind, placebo-controlled trials in androgenetic alopecia.

Other names for this medication:
Dutasteride, Deetor, Duodart, Duprost, Dutagen, Dutas, Dutasterida, Dute, Veltride,

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Dutas comes as a capsule to take by mouth. It is usually taken once a day with or without food. Take Dutas at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Dutas exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the capsules whole; do not open chew, or crush them.

Your symptoms may improve after you have taken Dutas for 3 months, but it may take 6 months or longer for you to see the full benefit of Dutas. Talk to your doctor about how you are feeling during your treatment.

Dutas may control your symptoms but will not cure your condition. Continue to take Dutas even if you feel well. Do not stop taking Dutas without talking to your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

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Detailed investigations revealed that he was suffering from multiple myeloma in which arthritis was a musculoskeletal complication of the disease. Structure-based prediction of the conductance properties of ion channels.

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We report a case of a 3-year-old boy with this rare infection that unravelled the diagnosis of CGD. Diagnosis of left atrial tumors by coronary angiography and left ventriculography. Physicians need to choose a prescription dose that provides an optimal middle ground between optimizing AVM obliteration with high radiation doses and limiting complication risks with the lowest doses. Thus cardiac valve morphology and function should be routinely assessed and reported on coronary CT angiography examinations. There were 446 women who ovulated in response to the treatments among the entire 626 participants.

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The small sample size dictates that additional experimentation must be performed before definitive conclusions can be drawn. The sequence of events leading to the internalization and degradation of a particle is conserved in D.

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Disease complexity within individuals and heterogeneity among individuals, even genetically identical individuals, is driven by stochastic execution of a complex inherited program. The Chicago Heart Health Curriculum Program (CHHCP) is a comprehensive, cardiovascular disease, risk-reduction program designed for a multiracial urban population of sixth-grade students and their families. Finally, important areas for future research in speckle tracking are briefly summarized. Ontogeny and localization of TGF-beta type I receptor expression during lung development. A total of 120 patients were enrolled in this study, dividing randomly into three groups: bronchial arterial infusion (BAI), traditional vein chemotherapy and BAI plus CIK.

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Discovery of novel, potent, and selective small-molecule CCR5 antagonists as anti-HIV-1 agents: synthesis and biological evaluation of anilide derivatives with a quaternary ammonium moiety. These results suggest that cells infected with the dl331 mutant develop a translational block at the level of GEF-catalyzed guanine nucleotide exchange and that this block is most likely established through phosphorylation of the alpha subunit of eIF-2.

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Here we will review recent discoveries elucidating HTLV-1 mediated manipulation of host cell miRNA profiles and examine the impact on pathogenesis, as well as explore future lines of inquiry that could increase understanding in this field of study. Current methods for cervical spine movement evaluation: a review. The medical social risk factors of developing the iron-deficiency anemia in pregnant women Hypothermia (29 C) resulted in an increase in mean survival time comparable to that in barbiturate-treated animals. Subclinical endometritis and its impact on reproductive performance in grazing dairy cattle in Argentina.

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This methodology, widely used for synthetic polymers, is proposed to better reflect the crystalline content of starches than the method normally used, in which it is assumed that relatively perfect crystalline domains are interspersed with amorphous regions. Lipolysis of apoprotein-free phospholipid/triglyceride emulsions also resulted in enhanced binding of CETP to the emulsion particles.

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With increasing score, doctors recommend taking an antimicrobial. These results indicate that seroprotection following primary vaccination with MenACWY-TT extends more than 3 years. The significance of yellow-body enucleation in the development of ovarian adhesions in cattle

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Rate of learning of the conditioned avoidance reflex in rats with various exploratory activity. Residential mobility in a cohort of primiparous women during pregnancy and post-partum. Initial qualitative estimate from the survey on the stay of severely mentally retarded children the public service hospitals of Paris Adaptation to deterministic force perturbations during reaching movements was extensively studied in the last few decades.

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Gas chromatography-mass spectrometry was used to determine the microbial contents of building materials subjected to water damage in a laboratory experiment and of materials collected from houses affected by water during the flood in Klodzko in south-western Poland, July 1997. evansi) and parasite detection tests (micro-Haematocrit Centrifugation technique, Giemsa stained blood smears, microscopic examination of lymph node aspirates and mouse inoculation). Some aspects of the toxicity and metabolism of thiamine administered at high doses

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Family-based designs enable assessment of genetic associations without bias from population stratification. Evaluation of the secretory activity of the adrenal cortex and gonads in women with epilepsy. However, diabetes exerts a much stronger effect on hip fracture risk in younger than older individuals which needs to be considered in hip fracture prediction. We aimed to assess knowledge among patients attending an outpatient genitourinary clinic in Scotland. Tumor antigen analysis in neuroblastoma by serological interrogation of bioinformatic data.

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The pilot project described here took the form of action research, focusing on dementia awareness education for nurses on acute wards and in accident and emergency departments. The evolution of the fractional excretion of urea as a diagnostic tool in oliguric states. Tracer quantities of colloidal 198Au were used to estimate the hepatic blood flow in normal children and in children with active or progressive chronic hepatitis and also to obtain scintigrams of the liver.

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The healing process was monitored clinically and ultrasonographically. TFAS restored range and quality of motion at the operated segment to intact values and restored near-normal motion at the adjacent segments. This report presents two cases of ulcerative EGC in two males, 73- and 80-year-old, with severe fibrosis.

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Morphological and cytochemical aspects of vaginal Candida albicans. The development of a biomarker of exposure based on the evaluation of the human antibody response specific to Anopheles salivary proteins seems promising in improving malaria control.

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In the present study, three known stressors, noise, cold and behavioral modification, were employed in evaluating the effects of stress on limb asymmetry. Treatment of hiatal hernia with esophagitis in a patient using esophageal speech after laryngectomy. briggsae lineages suggests that self-fertilization is unlikely to have evolved more than approximately 4 million years ago, which is less than a quarter of the time since they shared a common ancestor with outcrossing species. Gender specific effects on human eating have been previously reported.

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In addition, the molecular mechanism of action was investigated. The substitution pattern at the lower rim also affects the harmonic frequencies at the bottom of the potential well and at the top of the barrier. The fluorescence lifetimes of the single molecules were extended up to 5.5 times (28.6 ns) by the PBG effect. Hygienic care was improved and spasticity-related pain was reduced. The results suggest that tracking is vastly improved by using a closed-loop system to control muscle length, and that load does not affect the quality of signal tracking as measured by standard control system analysis methods.

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Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration. A total of 19 primer pairs produced scorable bands in the R pool. 34 cases of chronic hepatitis B were treated by bicyclol tablets for 24 weeks.

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Herein, the immune-mediated cell response to hepatitis C antigens was evaluated by adoptive transfers of carboxyfluorescein succinimidyl ester (CFSE) labelled splenocytes from HCV immunized mice into HCV transgenic mice. Higher Dbil level is associated with greater stroke severity but not outcome among ischemic stroke patients, possibly reflecting the intensity of initial oxidative stress.

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CC49-TCO(2) was administered to healthy mice to determine its blood clearance and the in vivo stability of the TCO. People with TBI are more likely to gain employment when they are aware of their cognitive deficits and abilities. To explore possible mechanisms of this translational control, the polysomal distribution of SCP mRNA was compared at the maximum and minimum points of SCP synthesis. The tropoelastin-binding site was localized to a region beginning at the glycine-rich and proline-rich regions of fibrillin-2 and fibrillin-1, respectively, and continuing through the second 8-cysteine domain. Targeting gene expression to the female larval fat body of transgenic Aedes aegypti mosquitoes.

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The collagen inhibitor D-penicillamine was evaluated as a potential radiation reaction preventive agent by studying its effect on deaths attributed to pulmonary damage in mice. The data on food frequency use indicated that the meal patterns of these households could not provide sufficient nutrients for individual family members. Dedicated algorithms were set up for the identification of the prevalent therapeutic hypotheses based on the available evidence and for ranking treatments based on the molecular profile of individual patients. After prenylation, the last three residues of CAAX proteins are clipped off by an endoprotease of the endoplasmic reticulum.

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Room temperature emission spectra of Tb(III) in a variety of environments have been examined under relatively high resolution. Cultured vascular EC, derived from the human placenta (HPEC), may be helpful for studying their specific function in the fetoplacental unit, such as in the control of maternofetal traffic. Acute puerperal inversion of the uterus is an uncommon but potentially fatal obstetric complication.

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Lactation insufficiency has many aetiologies including complete or relative prolactin deficiency. The uptake of newly synthesized plasma lipids from intraportally injected palmitate 1(-14)C by heart, kidney and adipose tissues of rats fed 33 mg retinol for 2 days have been studied. After the radical nephrectomy of the left kidney, hypercalcaemia remitted but reappeared 11 months later. The application of totally implantable venous access systems (VAS) started in 1982, in the United States of America, where at present 500,000 devices are implanted annually. Clinical nursing of patients with heart failure treated by vasodilators

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Effects of soil water table regime on tree community species richness and structure of alluvial forest fragments in Southeast Brazil. Although both augmenting and lifting the breast in a one-stage operation is gaining in popularity, its safety and its efficacy are still under debate and merit deeper evaluation. Canine interstitial nephritis with special reference to glomerular lesions and filariasis. When indicated, immunosuppressants and even anti-TNF-alpha agents can be used in the carefully monitored HIV patient.

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Skiagram of hand joints showed periosteal apposition without any periosteal reaction of long bones. Supplementary administration of oral prednisolone could shorten the duration of pain. Analysis of recreational drug samples obtained iv acyclovir in pregnancy from patients presenting to a busy inner-city emergency department: a pilot study adding to knowledge on local recreational drug use. RB status governs differential sensitivity to cytotoxic and molecularly-targeted therapeutic agents.

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Most infants with PHACES association have segmental hemangiomas of the head or neck. Spectrophotometric, colorimetric and volumetric determination of meprobamate and mebutamate Understanding the basic principles of palliative care can aid emergency department staff in identifying patients who could benefit from palliative care services and in managing the challenging situations that arise when such patients present to the hospital for care.In zindaclin gel erfahrungen beim this article we present the overall philosophy of pediatric palliative care, describe key elements of quality palliative care, and identify additional referral sources readers can access for more information. The effect of the dilution of the serum, circulating insulin and extraction of free and total insulin was evaluated.

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Because of its relevance to the functioning of the central nervous system, brain-derived neurotrophic factor (BDNF) has been implicated in the pathogenesis of different neuropsychiatric diseases. The anomalous vein was divided and anastomosed directly to the left atrium using a vascular technique alventa drug store that produced an orifice larger than the vein diameter. Evaluation and significance of kinetic parameters governing function of protein synthesis initiation factors eIF-2 and eIF-2B. Additionally, retraction of the EPEC bundle forming pilus stimulates directed elongation of nearby microvilli.

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