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Topiramate is a prescription drug. It comes in four forms: immediate-release tablets, immediate-release sprinkle capsules, extended-release capsules, and extended-release sprinkle capsules. All forms are taken by mouth. Topiramate oral tablet is available as the brand-name drug Topiramate. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug. This drug may be taken in combination with other drugs to treat epilepsy.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Topiramate is used alone or with other medications to prevent and control seizures (epilepsy). This medication is also used to prevent migraine headaches and decrease how often you get them. Topiramate will not treat a migraine headache once it occurs. If you get a migraine headache, treat it as directed by your doctor (such as by taking pain medication, lying down in a dark room). Topiramate is known as an anticonvulsant or antiepileptic drug.

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To determine whether concurrent chemoradiotherapy (CCRT) can improve the survival rate of high-risk uterine cervical cancer. He was successfully treated with partial nephrectomy following selective embolization of the feeder artery. Delayed presentation to hospital is the main factor limiting the use of thrombolysis in acute stroke, but additional patients would be treated if those with no contraindication, advanced age or rapidly recovering stroke were considered as eligible. In this review, we discuss the adverse effects associated with aflibercept (VEGF Trap), focusing on vascularassociated hypertension, proteinuria, hemorrhage, and thrombosis, and further discuss the mechanisms, significance, and potential management of these adverse effects.

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These new results reduce transition probability uncertainties and yield more accurate derived stellar abundances. Careful attention to these four phases of management should lead to highly satisfactory control of the syndrome of gout. The sensitivity of the IOL power calculation to an axial length measurement error is increased at 4 to 14 D/mm error in axial length in children compared with 3 to 4 D/mm error in axial length in adults. The study examined the influence of different types of enhanced system support on user performance during the management of a central heating system. DH and JH usage in murine fetal liver mirrors that of human fetal liver.

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The cGMP analogue 8BrcGMP mimicked the effects of NO donors suggesting that the effects of NO are mediated by cGMP. Certification of standard reference materials containing bitter orange. We present a case of suspected hepatic encephalopathy that did not respond to standard empiric therapy and was eventually diagnosed as non-convulsive status epilepticus of complex partial type. The characterization of human amnion epithelial and mesenchymal cells: the cellular expression, activity and glucocorticoid regulation of prostaglandin output.

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Epidemiological particularities of viral hepatitis at child age. The reaction and growth mechanisms of ZnO twin-cones were investigated by X-ray diffraction, UV-visible spectra, infrared and ion trap mass spectra, and transmission electron microscopy.

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injection either as a single dose of 1 mg/g (only 0.5 mg/g for RGW-608) or in 36 fractions of 0.15 mg/g over 18 days (only 4 fractions in 2 days for RGW-608). A high percentage of the individuals who consult respiratory medicine specialists are working adults, and these patients often complain that dyspnea on exertion hinders their ability to do their job.

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In addition, disability is likely to be more common in rural compared with urban areas. Exercise therapy for bone and muscle health: an overview of systematic reviews. After typing by neutralization test, the VP1 gene of the isolates were amplified by RT-PCR and sequenced. This study demonstrated that chronic exposure to a mixture of PCBs and OCPs can increase the risk for MetS within the low-dose background exposure range of POPs.

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All biochemical parameters were analyzed in the Central Laboratory of our hospital by standard validated methods. Gender-based violence (GBV) is prevalent among, though not specific to, conflict affected populations and related to multifarious levels of vulnerability of conflict and displacement.

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A DNA subclone (pPE-4000) derived from the lambda B4 interferon-beta-related human genomic DNA clone was used as a probe in blot-hybridization experiments of DNA from a panel of human-rodent somatic cell hybrids containing overlapping subsets of human chromosomes. dose of either 1200, 1800 or 2400 mg N-butyl-N-(4-hydroxybutyl)nitrosamine over a period of six weeks.

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The decrease in enzymic activities and nucleotide concentrations progressed with time. The existence and properties of the newly discovered particle may also have consequences beyond the standard model itself. The early research described that adrenocorticotropic hormone (ACTH) release from mouse pituitary tumor AtT-20 cells was regulated by histamine H(3) receptors.

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SEB-induced cytokine production and proliferation in vitro were significantly reduced by the hyaluronic acid blocking peptide, Pep-1. It has been claimed in some studies it is not related to prognosis as in our study, and in some studies it has been claimed that it is a good prognostic factor whereas in some studies it has been claimed as being a factor for worse prognosis. Carcinoma of the breast and hormone replacement therapy for osteoporosis.

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The control of cell number in the lumbar ventral horns during the development of Xenopus laevis tadpoles. Tooth loss, pocket depth, and HbA1c information collected in a dental care setting may improve the identification of undiagnosed diabetes. Angiographic interpretations were compared with the pathologic findings of 75 patients undergoing nephrectomy for renal carcinoma. Electrocatalytic reduction of ortho nitrobenzaldehyde using modified aluminum electrode and its determination.

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In case of structural templates absence, heuristic structural information is incorporated instead. Results were discussed in terms of the impact of social variables on eating behavior, and the theoretical importance of weight consciousness and pereceived social pressures in understanding correlates of obesity. Using a simple and relatively inexpensive technique, blood was salvaged during major thoracic and cardiovascular surgery in 34 cases. Electron flow via thiols is a theme with many variations in all kingdoms of life.

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The blood level did not correlate to the drug disappearance from the intestinal lumen. Importance of static perimetry in the examination of colloid macular degeneration Therefore, we hypothesized that the chromatin configuration and histone methylation could also change in old GV oocytes. Infants born preterm commonly suffer from a combination of hypoxia-ischemia (HI) and infectious perinatal inflammatory insults that lead to cerebral palsy, cognitive delay, behavioral issues and epilepsy. Polyunsaturated fatty acids (PUFA) and plasmalogens are the two main substrates for lipid peroxidation in the pulmonary surfactant.

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In both conditions, words were visually presented on the recognition test, and half were preceded by brief repetition primes. Prenatal exposure of rats to antidepressants enhances agonist affinity of brain dopamine receptors and dopamine-mediated behaviour. The Anagram Complexity X Slide Complexity interaction was significant: the complexity of the slides showing the most positive change scores was inversely related to the complexity of the anagrams attempted. Using this method, we were able to measure the volume ingested in single sips of an individual, and monitor the absorption of food with high temporal resolution.

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Although this process is generally tightly regulated by subsequent synthase activity, little is known about how the glutaminase is inhibited in the absence of an activating signal. Type I signal peptidases (SPases) are required for the removal of signal peptides from translocated proteins and, subsequently, release of the mature protein from the trans side of the membrane. Distribution of inorganic pyrophosphatase in some marine invertebrates of the Japan Sea.

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Using chromium(51) edetic acid clearance as a gold standard, children with spinal dysraphism and slightly to moderately reduced renal function may remain undiagnosed if cystatin C is used for evaluation. Characterization of the pH-dependent dissociation of a multimeric metalloprotein Streptomyces rubiginosus xylose isomerase by ESI FT-ICR mass spectrometry.

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The aim was to determine the long-term outcome for patients with FIGO stage IV epithelial ovarian carcinoma (EOC) treated with intraperitoneal (IP) chemotherapy after second-look assessment. Data were compared using independent t-test or analysis of variences. In the present study, glutathione was demonstrated to play a dual role on selenite (Se)-induced oxidative stress and apoptosis in human hepatoma HepG(2) cells. It generates malformations such as oedema, brain deformities, a shortened and bent tail, and bipartite axiation of the posterior trunk.

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Principles and performance in the determination of GOT and GPT transaminases under reaction-optimal and substrate-optimal conditions Mitochondria are the focal point for a variety of pro- and anti-apoptotic stimuli. Physical work capacity under different levels of measured stress in relation to type-A personality in intellectual workers

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The aim of our study was to evaluate bone quality by quantitative ultrasound (QUS) at the phalanges in 129 monozygotic twin couples, outlining the differences between growing subjects and adults. Effect of megestranol and prostaglandin F2 alpha on the maturation and membrane potentials of human ovocytes

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acetatoxydans fhs2 cluster encodes Wood-Ljungdahl pathway enzymes, which are also known to be involved in C1 carbon metabolism. The program was revised after two years to streamline the data entry process and to include three Patient Reported Outcome Measurement Information System (PROMIS) questionnaires measuring pain, general health, and physical functioning. Frequent oral PPI may be able to replace the currently recommended intravenous bolus plus infusion PPI therapy in patients with bleeding ulcers, although the possibility that intravenous PPIs are superior cannot be definitively excluded given our relatively wide confidence intervals.

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A defective function of the antigen-presenting cells may represent one of the ways used by cancer cells to escape the immune response. Possible mechanism for regulation of inflammatory responses with the S100A8/A9 protein Blood stream infections of abdominal origin in the intensive care unit: characteristics and determinants of death. We found out that it is important for people with a learning disability to have good things in their lives, but it is also important to be enabled to access these good things.

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Goal-directed administration of blood products based on the results of viscoelastic haemostatic assays was associated with reduction in allogeneic blood product transfusions in trauma, cardiac surgery, and liver transplantation cases. The central stalk contains the gamma and epsilon subunits and is thought to function in rotational catalysis as a rotor driving conformational changes in the catalytic alpha(3)beta(3) complex. A significant proportion of patients undergoing surgery for ankle fracture experience postoperative complications and delayed return to function.

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Although mean IOP during the dark period was significantly higher than the light period in both strains, the magnitudes of light-dark IOP elevation differed. We recommend that invertebrate testing is used to advance the level of knowledge in nanoecotoxicology through standardized short-term (lethality) tests with invertebrates as a basis for investigating behaviour and bioavailability of engineered nanoparticles in the aquatic environment. the purpose of this study was to describe the incidence of serious bacterial infections in febrile outpatient pediatric kidney transplant recipients and to assess the utility of using white blood cell indices to identify patients at low risk for bacteremia. DCX is essential for neuronal migration because humans with mutations in the DCX gene exhibit cortical lamination defects known as lissencephaly in males and subcortical laminar heterotopia (or double cortex syndrome) in females. However, there is no much data about the in vivo functional consequences of this injury or the long time observed CyA-induced renal vasoconstriction.

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The IMGT Scientific chart rules, based on the IMGT-ONTOLOGY concepts, were the prerequisites for the implementation of the IMGT/V-QUEST and IMGT/JunctionAnalysis tools. Facial nerve injury during surgery of the temporomandibular joint: a comparison of two dissection techniques.

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Medical treatment in most patients or coronary artery bypass graft in high risk situations may be preferable if the cancer is being actively treated. This clinical study examined the diagnostic potential of porphyrin fluorescence in patients with cervical intraepithelial neoplasia Grade 1-3 (CIN 1-3). The results of these studies are presented and some of the requirements necessary for underground installations described, including rock conditions, depth of facilities, and economics.

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Previously, we showed that the phosphatidylinositol-3 kinase (PI(3)K) pathway mediates the anti-apoptotic effects of IGF-I in human neutrophils independently of its down-stream target Akt. Early stage phyllosoma larvae of the spiny rock lobster Jasus edwardsii were examined for swimming speed, feeding, oxygen consumption and nitrogen excretion as instantaneous performance indicators when exposed to different irradiance levels. Molecular mechanisms of changes in ionic permeability of an electrically excitable membrane. Helicobacter pylori remains a global health hazard, and vaccination would be ideal for its control. Startle elicited electrically from the VCN, VAS, and VLL was also significantly increased by the light.

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Usefulness of magnetic resonance imaging for congenital prepubic fistula. The nature of portfolio analysis and the steps in a multi-factor portfolio analysis are reviewed along with the characteristics of the research setting.

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Finally, these alarms must work both indoors and outdoors, and the user should not have to worry about where he/she is or who is acting on an alarm. Salutary antiarrhythmic effect of combining a K channel blocker and a beta-blocker in a canine model of 7-day-old myocardial infarction. Here, we present a comparative analysis of social amoebae mitochondrial genomes using D.

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Study of afferent nerve terminals and fibers in the gerbil cochlea: distribution by size. To compare the effects of an interdisciplinary comprehensive care programme with those of subacute care and usual care programmes on health-related quality bijur delimon india pvt ltd bangalore map of life (HRQoL) for elderly patients with hip fracture.

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