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Penile erection is caused by the engorgement of the penis with blood. This engorgement occurs when the blood vessels delivering blood to the penis increase the delivery of blood and the blood vessels carrying blood away from the penis decrease the removal of blood. Under normal conditions, sexual stimulation leads to the production and release of nitric oxide in the penis. Nitric oxide then activates the enzyme, guanylate cyclase, which causes the production of cyclic guanosine monophosphate (cGMP). It is the cGMP that is primarily responsible for the erection by affecting the amount of blood that the blood vessels deliver and remove from the penis. Caverta inhibits an enzyme called phosphodiesterase-5 (PDE5) which destroys the cGMP. Thus, Caverta prevents the destruction of cGMP and allows cGMP to accumulate and persist longer. The longer cGMP persists, the more prolonged the engorgement of the penis. The FDA approved Caverta in March 1998.

Other names for this medication:
Sildenafil, Aurogra, Avodart, Caverta, Cenforce, Eriacta, Intagra, Kamagra, Lovegra, Nizagara, Penegra, Revatio, Silagra, Sildalis, Sildenafila, Sildenafilo, Sildigra, Suhagra, Veega, Viagra, Vigora, Womenra, Zenegra,

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Caverta is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, Caverta works by increasing blood flow to the penis to help a man get and keep an erection. This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, syphilis). Practice "safe sex" such as using latex condoms. Consult your doctor or pharmacist for more details. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. Caverta is also available in other brands and strengths for treating high blood pressure in the lungs (pulmonary hypertension). Do not take this medication with any other product that contains Caverta or other similar medications for erectile dysfunction-ED or pulmonary hypertension (such as tadalafil, vardenafil).

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