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Sumetrin (Sumatriptan)
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Sumatriptan

In this systematic review we present information relating to the effectiveness and safety of the following interventions: baclofen (oral), botulinum toxin (intramuscular), capsaicin (intranasal), chlorpromazine, civamide (intranasal), clonidine (transdermal), ergotamine and dihydroergotamine (oral or intranasal), gabapentin (oral), greater occipital nerve injections (betamethasone plus xylocaine), high-dose and high-flow-rate oxygen, hyperbaric oxygen, leuprolide, lidocaine (intranasal), lithium (oral), melatonin, methysergide (oral), octreotide (subcutaneous), pizotifen (oral), prednisolone (oral), sodium valproate (oral), Sumetrin (oral, subcutaneous and intranasal), TCAs, topiramate (oral), verapamil, and zolmitriptan (oral).

Other names for this medication:
Sumatriptan, Imitrex, Amigrenex, Amigrenin, Cinie, Forcet, Formigran, Imigran, Imigrane, Imiject, Migranol, Migrastat, Migrex, Nograine, Sitran, Suma, Sumagen, Sumamigren, Sumatab, Sumatran, Sumetrin, Sumigran, Suminat, Sumitran, Sumitrex, Suvalan, Zumo,

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Sumetrin injection is used to treat acute migraine attacks and cluster headaches in adults. Sumetrin works in the brain to relieve the pain from migraine headaches. It belongs to the group of medicines called triptans.

Many people find that their headaches go away completely after they use Sumetrin. Other people find that their headaches are much less painful, and that they are able to go back to their normal activities even though their headaches are not completely gone. Sumetrin often relieves other symptoms that occur together with a migraine headache, such as nausea, vomiting, sensitivity to light, and sensitivity to sound.

Sumetrin is not an ordinary pain reliever. It will not relieve any kind of pain other than migraine headaches. This medicine is usually used for people whose headaches are not relieved by acetaminophen, aspirin, or other pain relievers.

Sumetrin has caused serious side effects in some people, especially in those who have heart or blood vessel disease. Be sure that you discuss with your doctor the risks of using this medicine as well as its benefits.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Solution
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Simple method for monitoring flow rate during gravity perfusion. The developmental expression of Cux1 in the cerebellum and its action in cell lines support a role in granule cell and medulloblastoma proliferation.

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When endothelial progenitor cells (EPC) isolated from human peripheral blood were cultured with supernatant from SHH-transfected 293 cells or pancreatic cancer cells, mRNA levels of vascular endothelial growth factor (VEGF), stromal cell-derived factor-1 and angiopoietin-1 were significantly increased, whereas no such induction was observed in human umbilical vein endothelial cell (HUVEC) and human dermal microvascular endothelial cell (HMVEC). Thus, our culture techniques can serve as useful tools to study mechanisms of differentiation by modulating the phenotypic potential of osteogenic cells. Radiologic evaluation revealed extension into the infratemporal fossa and confirmed that the tumor was invading into pterygoid muscle. In cancer, arginase-expressing myeloid derived suppressor cells (MDSCs) deplete arginine, impair T cell receptor CD3 zeta-chain expression and T cell function and are linked to poor clinical outcome, but their role during acute human infectious disease and in particular sepsis remains unknown. Matrix isolation IR spectroscopic and ab initio studies of C(3)N(-) and related species.

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Limited exposure or experience in EEG interpretation during training translates to persistent inexperience in clinical practice. A beta-1,3-glucan binding protein (betaGBP) specific for laminarin (a beta-1,3-glucan) was detected for the first time in a mollusc, Perna viridis. Phage display of antibody fragments has allowed access to large collections of different phage antibodies, created by cloning antibody V-genes from B-cells. Nanoparticles can form unique cavity-like structures in core-shell type assemblies of block copolymers through the cooperative self-assembly of nanoparticles and block copolymers.

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Light and electron microscopic identification of the histamine-storing argyrophil (ECL) cell in murine stomach and of its equivalent in other mammals. The changes in the liver on the use of carminomycin, rubomycin and olivomycin in single doses or during the treatment course were reversible, while on the use of bruneomycin they preserved to the end of the experiment.

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The authors suggest that using linear baseline correction as the spectrum processing method to improve Chla inversion accuracy in turbidity water without algae bloom. It had been proved that the removal ratios related to the adsorption and photocatalysis capability of the composites and were influenced by US and UV irradiation, the reaction times, the reaction temperatures, the initial pH values, the dosages and the initial MO solution concentrations. The clinical symptoms using global symptom score (GSS) and electrophysiological parameters were assessed at baseline and four weeks after the intervention. Unfortunately, owing to the exposure of puppies to infections with either canine parvovirus (CPV) or distemper virus (CDV) after the intervention of the vaccinators, owners are reluctant to vaccinate puppies against rabies.

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RNA-Seq based global transcriptomic analysis provided a comprehensive view of cellular response to ethanol exposure. Increased morbidity in low-birth-weight survivors with severe retrolental fibroplasia. A biocatalytic electrode activated by pH signals was prepared with a multilayered nanostructured interface including PQQ-dependent glucose dehydrogenase (PQQ-GDH) directly associated with the conducting support and glucose oxidase (GOx) located on the external interface. This article describes the changing resistance mechanisms that allow bacteria to circumvent antibiotics and how multidrug-resistant bacterial infections can spread within hospitals, among health care facilities, and across national borders.

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The anatomical location of the skin eruption was most common in the areas of the fifth cranial nerve, middle and lower trunk and thigh. Available evidence suggests several mechanisms by which cigarette smoke might accelerate the osteoporotic process, including smoke-induced lowering of the pH of bone tissue resulting in absorption of bone salts. One peptide derivative in particular (E23A) displayed superior inhibition of complement activation in multiple assays of classical complement pathway activation.

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The serum IDO levels of postoperative breast cancer patients with a high number of bone metastases were lower than those of patients with a single metastasis lesion. Direct binding measurements showed the existence of a tight binding site, with a dissociation constant of the same order of magnitude as the inhibition constant. Modification of histone binding in calf thymus chromatin by protamine.

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Diaphyseal tissue was found to have greater elastic modulus and hardness than metaphyseal tissues for all microstructures, whereas interstitial elastic modulus and hardness did not differ significantly between metaphyses. Immunohistochemical staining of thirteen cases with antisera to lysozyme, alpha 1-antichymotrypsin and S-100 protein has provided no evidence to support either a histiocytic or neuroectodermal origin for these tumours. A detailed investigation of PM2.5 chemical composition and source apportionment analysis showed that the increase in PM2.5 mass was driven mainly by organic carbon (OC).

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Incorporating the constraints into the RLS method leads to the constrained regularized least-squares (CRLS) method, which is realized by means of an active set algorithm of quadratic programming. On the effect of various high radiation doses on the amino acid metabolism

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Endoscopic resection of gastric subepithelial tumors (SETs) carries a high risk of perforation. Psychotherapeutically oriented treatment of schizophrenia: results of 5-year-follow-up. Plasma homocysteine (Hcy) is an important risk factor for various diseases. The reasons for this are most likely technical: To demonstrate this circulation, a large volume of contrast medium must be used and, because of the low flow velocity in the numerous wide collaterals, delayed films are also necessary.

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A comparison of serum concentrations of biochemical bone turnover markers in patients with osteosarcoma with good and poor prognosis Under physiological conditions, these two neuronal intermediate filaments show different expression patterns in sensory neurons. Feeding ecology, food availability and ranging patterns of wild hamadryas baboons at Filoha. The intestinal epithelium is continuously and rapidly renewed by a process involving cell generation, migration, and differentiation, from the stem cell population located at the bottom of the crypt to the extrusion of the terminally differentiated cells at the tip of the villus.

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Inducible nitric oxide synthase (iNOS) expression upregulates p21 and inhibits vascular smooth muscle cell proliferation through p42/44 mitogen-activated protein kinase activation and independent of p53 and cyclic guanosine monophosphate. Image analysis included determination of malignancy within the peritoneum (11 sites), lymph nodes (10 sites), and hepatic parenchyma.

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Collectively, the data add new evidence for the role of beta1 glycosylation/sialylation in the regulation of integrin functions. This practice appears to have a lower morbidity than that associated with arterial reconstruction.

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Transcranial Doppler ultrasonography-directed intravenous glycoprotein IIb/IIIa receptor antagonist therapy to control transient cerebral microemboli before and after carotid endarterectomy. Correlation coefficients were used to examine the relationship between variables.

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We employed fully optimized linear discrimination analysis to maximally separate the multi-electrode responses to tones and phonemes, and classified the response to elongated phonemes. Treatment with BAC-containing anti-allergic drugs and BAC alone resulted in increased paracellular permeability and loss of transcellular barrier function as indicated by TEER measurement and rose bengal assays. Closed endotracheal suction interferes with mechanical ventilation received by infants, but the change to ventilation may be different when ventilator modes that target expired tidal volume (VT(e)) are used.

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The observed increases in CMV seed transmission, and reductions in virus accumulation and virulence in vertically passaged viruses were due also to reciprocal host adaptation during vertical passages, which additionally reduced virulence and multiplication of vertically passaged viruses. Malignant mesothelioma is a tumor which may be associated with elevated hCG concentrations. We conclude that mitoxantrone, at a dose of 12 mg/m2/day X 5, is effective therapy for ANLL. Apolipoprotein B is the most frequently occurring dyslipidaemia in type 2 diabetes.

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Expression of Bcl-2 family proteins and association with clinicopathological characteristics of oral squamous cell carcinoma. Association of genetic polymorphisms in CD40 with susceptibility to SLE in the Korean population.

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Clinical data of 28 patients with CSP in Peking Union Medical College Hospital from January 1994 to April 2007, including age, interval from the last cesarean delivery to diagnosis, clinical presentation, location of the lesion, process of diagnosis and treatment, outcome, and follow-up, were retrospectively analyzed. Substance use outcomes 51/2 years past baseline for partnership-based, family-school preventive interventions. The deposit was identified as magnesium hydroxide and this fouling was more important on the cation-exchange membrane situated close to the cathode. Decreases in EAAC1 and GLT-1 mRNA levels would represent either neuronal changes due to the delayed neuronal death or a putative protective down-regulation of these transporters to decrease the amount of glutamate inside the neurons, which would decrease their glutamate release. Radioimmunoassay of the incubation mixtures showed that the rapid degradation of both amino- and carboxy-terminal regions of the hormone was prevented by histone.

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In the control condition, only the latter request was addressed. While purvalanol treatment activated apoptosis and autophagy in HCT 116 cells, roscovitine was only effective on caspase-dependent apoptotic pathway. beta-Adrenoceptor activity of rat thoracic aorta decreased with the increasing age of the animal.

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He was given a diagnosis of primary cutaneous adenoid cystic carcinoma with metastatic lesions to multiple lungs and left tibial bone and then given chemotherapy combining CDDP plus VNR as the first treatment in December 2008. Remantadine suppressed the functional activity of monocytes and increased their lesion by the virus, thus creating favorable conditions for virus persistence in monocytes. This interaction requires both the p11-binding N-terminal domain of A2 and the C-terminal domain of p11. Four brands of endodontic paper points were subjected to tests for sterility, antibacterial activity, and suitability as vehicles for bacteriological sampling procedures. Airway hyperresponsiveness, serum allergen specific antibody levels, cytokine production by splenocytes, and bronchoalveolar lavage fluid were examined.

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The possible role of glycosaminoglycans in synaptosomes is also discussed. Temporal intensity and chirp characterizations demonstrate that the pulses exhibit characteristic of low RIN, and are chirp- and pedestal-free.

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The effect of human growth hormone on the carbohydrate units in arterial basement membrane-like material. A total of 98,391 patients in the 2-yr pre-rapid response team and 157,804 patients in the 3-yr post-rapid response team implementation were evaluated.

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Gevokizumab in type 1 diabetes mellitus: extreme remedies for extreme diseases? Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/Deuterium exchange (sHDX) coupled to high-resolution mass analysis of the digested protein or protein complex.

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Increased content of neuropeptide Y in human pheochromocytoma cell cultures. floridana strain and the formation of azygospores and zygospores by a Norwegian N. Preparation and characterization of biodegradable paclitaxel loaded alginate microparticles for pulmonary delivery. Herein reported is a case where historical omission of imiquimod use for actinic keratosis complicated the histologic interpretation. Anomalous oxygen uptake from isolated chloroplasts inhibited in photosystem II and without external electron donors.

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All of the recovered calmodulin-dependent kinase activity in microtubules eluted in a single protein peak. A key step in the future development of non-viral gene therapy will be the design and development of synthetic systems for active delivery of DNA to the nucleus.

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Plant origin of Okinawan propolis: honeybee behavior observation and phytochemical analysis. Hypertonic resuscitation improves neuronal and behavioral outcomes after traumatic brain injury plus hemorrhage.

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This article reviews aspects of asthma management in youngsters at a time of significant transition. There was insufficient evidence to determine whether general practitioners with a special interest (GPwSI) in respiratory care improved the diagnosis and management of mild-to-moderate COPD.

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We identified three variants associated with higher mitochondrial copy number and suggest several hypotheses for how these variants influence mitochondrial copy number by interacting with known regulators of mitochondrial copy number. The effect of narrowband UV-B treatment for psoriasis on vitamin D status during wintertime in Ireland.

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Conversely, the flapless method requires only minimal removal of soft tissue but is not suitable for all patients. The population consisted of 54 patients who had committed suicide and 50 patients who had not. Compared with other available therapies, a shorter survival rate was noted. Recent data show an increasing rate of venous disease, and increasing evidence supports a role for veins in systemic diseases.

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The authors report a case of an ectopic secreting choroid plexus in the oropharyngeal region of a neonate. Differential antagonism by dicyclomine, pirenzepine and secoverine at muscarinic receptor subtypes in the rat frontal cortex. Current status and future prospects of parenteral insulin regimens, strategies and delivery systems for diabetes treatment.

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Relying on this system for patient setup might be associated with significant setup errors. This paper suggests a novel approach to the blind focusing of the electromagnetic field for microwave hyperthermia.

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The identified systematic and random errors require an optimal clinical tumor volume to planning target volume margin of about 3 mm. In copper-deficient rats, oral intubation of copper increases the rate of ceruloplasmin synthesis without affecting general synthesis of plasma or liver proteins. Renal responses of the chilean toad, Calyptocephalella caudiverbera, and the mud puppy, Necturus maculosus, to mesotocin. Letter: Measurement of electrical potential difference across colonic mucosa in cystic fibrosis patients. An abnormal response of retinoblastoma cells (Y-79) to neurotrophins.

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Concerning the long-term efficacy, the paraplegia-triple-needling combined with the rehabilitation training achieves better result. Methylation profiles reveal distinct subgroup of hepatocellular carcinoma patients with poor prognosis. This case should make physicians aware of this infrequent iatrogenic disorder which is apparently increasing in its occurrence. The human transcript database: a catalogue of full length cDNA inserts. We discuss interesting structural parallels with the carbon tetrahalides.

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In vivo lipolytic effect of glucagon in warm-adapted and cold-adapted rats. Functional survival at hospital discharge was associated with shorter times to initial defibrillation and was decreased during each successive phase of the 3-phase model. Generally it is the last one to dilate when an internal hydrocephalus occurs, but it is the first to regress after inserting a drainage of the cerebrospinal fluid. In the presence of antioxidants such as 2,6-di-t-butyl-4-methylphenol (BHT) and octyl gallate thioesterification of oleic and elaidic acids with 1-tetradecanethiol as well as transthioesterification of methyl linoleate with 1-tetradecanethiol led to the corresponding geometrically uniform thioesters without radical-induced side reactions.

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This study aimed to identify urinary microRNAs (miRNAs) as biomarkers for FSGS disease activity. The mice in each group were sacrificed 20 min later and their stomachs, intestines, and colons were harvested immediately. The responses from the central 7.0 degrees arc of the visual field were measured, and changes in latency and amplitude were compared between the amblyopic, fellow, and normal control eyes. Thus past assumptions about equivalences between lasers must be reexamined. Occurrence of late coronary obstructions after arterial switch operation was often reported.

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No continuity was seen with the peripheral within the central nervous tissues by selective maturation of multipotential primitive reticular cells, a phenomenon consistent with the view that Schwann cells are mesenchymal in character. It is reasoned that in the first two cases the oxygen uptake arises from chlorophyll-photosensitized activation of oxygen to the singlet state and its consumption by exogenous or endogenous substrates. Epithelial morphogenesis: the role of vascularity in mesenchymal specificity.

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The protective effect of hulls on the occurrence of Alternaria mycotoxins in spelt wheat. Such structure could also doxin mercury drug job be used for wavelength demultiplexing with the center wavelength determined by the length of the bus waveguides and slits. Sensitivity analysis of the two PBPK model structures showed the importance of early time course data collection, and the impact of diffusion for kidney time course data description. Malignant tumours are characterised by distortion of their vessels.

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Scientists who sefdin tablet use the mouse model system have demonstrated that sex and age can influence a number of behaviors. Influencing factors of disinfection byproducts formation during chloramination of Cyclops metabolite solutions. Western blot analysis and immunofluorescence staining showed that p53 was localized in the nucleus of untreated cell and that after 48 h of hormone treatment, it was mostly localized in the cytoplasm. Effectiveness of ECG-gated magnetic resonance imaging in diagnosing cardiovascular diseases. The syndrome is also characterized by modularity, i.e., deficits of awareness in one domain (e.g., spatial perception) co-existing with spared functions in another domain (e.g., memory).

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Our analyses show lesflam dosage for infant that diabetes-related disparities affect not only people and their families but also the community that absorbs the costs associated with the disproportionate health care use that results from these disparities. When processing the less expected low typicality targets, younger - but not older - adults elicited a prefrontal positivity (500-900ms) that has been linked to processing consequences of having predictions disconfirmed. In this study Human ovarian carcinoma cell line SKOV3 and multidrug-resistant phenotype SKVCR cells were used and the roles of autophagy in radiation-induced cell death were analyzed. The elevated intraocular pressure (IOP) of primary open-angle glaucoma is caused by impaired outflow of aqueous humor through the trabecular meshwork.

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Six bile acid pairs were tested, and it was found that both conjugation and the number and disposition of hydroxyl groups influenced lamidat lamivudine tablets hepatic transport. Four variables--Reality Testing, Level and Quality of Object Relations, Affect Availability and Tolerance, and Motivation--were chosen for study and are discussed in detail. As proneurotrophins are a dominant form of gene products in developing and adult animals, it is imperative to understand their physiological functions in animals.

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The spectral differences were due to a decreased deshielding of the protonated nitrogen on the neighboring bicyclic ring protons, resulting in clonazepam nasal spray chemical shift changes. Anti-ICAM-1 blockade reduces postsinusoidal WBC adherence following cold ischemia and reperfusion, but does not improve early graft function in rat liver transplantation. Isolated mitochondria are widely used in metabolic and oxidative stress studies for neurodegenerative diseases.

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These observations suggested that these endoplasmic-/Golgi-derived vesicles behave as active autophagic organelles presenting probably a maturation process from compact morulae to blastocyst. Skull base meningiomas commonly present with cranial neuropathies. The antioxidant activities were measured by two models: 1,1-diphenyl-2- picrylhydrazyl (DPPH) radical scavenging activity and ferric reducing/ antioxidant power (FRAP). Disruption in an Fgf3, -10/Dlx5 hla-b5701 screening prior to abacavir prescription clinical and laboratory aspects signaling cascade is operant in molecular mechanisms of inner ear teratogenesis by excess RA. Leaders at an 852-bed community hospital planned an elaborate redesign that would reorganize units, revamp rooms, and update the exterior.

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Transient JMJD2B-mediated reduction of H3K9me3 levels improves reprogramming of embryonic stem cells into cloned embryos. While it is generally accepted that the best results are obtained if oesophageal continuity is established, this may be difficult to achieve. A total of 293 persons polyflam mirage iv scale with symptomatic typhoid fever who had Salmonella Typhi isolates and epidemiological information submitted to US public health departments and laboratories from June 1, 1996, to May 31, 1997. Our experience with surgical treatment of inguinal hernia in infants