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Topamac (Topiramate)
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Topiramate

Topamac is a unique antiseizure medication that is used in treatment of partial and generalized seizures. Topamac has been rarely associated with hepatic injury and largely when used in combination with other anticonvulsant medications. Topamac is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Topamac is also used to prevent migraine headaches but not to relieve the pain of migraine headaches when they occur.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Topamac is used alone or together with other medicines to help treat certain types of seizures (eg, partial seizures, tonic-clonic seizures, or Lennox-Gastaut syndrome). This medicine will not cure epilepsy and will only work to control seizures for as long as you continue to take it. It is also used to help prevent migraine headaches.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Capsule, Extended Release
  • Tablet
  • Capsule

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Severe peripheral sensory neuron loss and modest motor neuron reduction in mice with combined deficiency of brain-derived neurotrophic factor, neurotrophin 3 and neurotrophin 4/5. Four of the patients were diagnosed and treated with Shamblin type II tumor, one of the patients with type I. It is shown that integrated absorbance measurements over optimal limits of the C-H-stretching region are substantially more sensitive than those of the C-H-bending region.

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Cardiac rehabilitation services are comprehensive long term programmes designed to limit the physiological and psychological effects of cardiovascular disease (CVD), control cardiac symptoms and reduce the risk of subsequent CVD events by stabilising or partially reversing the underlying atherosclerosis process through risk factor modification. Clinical records of patients in a neonatal intensive care unit were reviewed to determine the efficacy of obtaining a urine culture in the detection of neonatal sepsis. Five flaps were used for coverage of the defects of the hand and fingers, whereas another 5 flaps were used for head and neck defects. It is now generally accepted that short-course radiotherapy (SCRT) and immediate surgery is associated with less early toxicity compared to conventionally fractionated chemoradiotherapy with delayed surgery. Low grade contractures under 15 degrees have been tolerated over many years.

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With proper planning, quality dual purpose equipment, appropriately trained staff, capable physicians, and strong leadership, an organization willing to embrace the challenge can build a truly extraordinary service. Laurasiatheria is one of the richest and most diverse superorders of placental mammals. Assessment and management of gastrointestinal toxicities and lab abnormalities related to targeted therapy. To investigate the enzymatic and chemical reactions in a regime of forced oscillations an apparatus has been constructed which permits to observe amplitude-frequency and phase-frequency characteristics of objects in the range of frequencies 10-2-10-6 c/s. Mediterranean diet and coronary heart disease: is obesity a link?

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To image nontransparent samples we have utilized a special type of scanning-probe microscope that is referred to here as a reflection scanning microscope. Subpontic osseous proliferation was documented in nine patients, but no conclusion about the etiology was made. pestis Tc proteins are highly expressed in the flea but are not essential for Y. These results suggest that HIV testing of TB patients is not universal, but rather selective, and is likely based on perceived risk factors for HIV as opposed to TB diagnosis alone.

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The aim of this study is to determine expression of ER (estrogen receptor) and AR (androgen receptor) in lung cancer, and evaluate the relationship between their expression and clinical or pathologic characteristics. Nestin expression in mesenchymal stromal cells: regulation by hypoxia and osteogenesis. Appointments later in week are less likely to be missed, finds study. Divalent cations cooperatively stabilize close membrane contacts in myelin. These results show the presence of many changes in islet transcriptome in T2D islets and underline the importance of the association between UPS alterations and beta cell dysfunction in human T2D.

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A four-element lens system is necessary to provide a satisfactory state of correction over a full field of 0.5 deg. Ets-1 may participate and play an important role in the regulation of follicular development, corpus luteum formation, maintenance, and regression. The effects of SCFA on the expression of hilA and invF-lacZY transcriptional fusions were examined to determine the potential role of SCFA in the pathogenesis of Salmonella typhimurium.

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A high-flux electron beam is focused on the inner surface by optimizing the shape of the bending magnet. Bowel dilation as a predictor of adverse outcome in isolated fetal gastroschisis.

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To determine the importance of the polymorphisms in the genes involved in maintenance of cellular redox balance, we performed a case control study in subjects from south and north India. Identification of APOH polymorphisms as common genetic risk factors for venous thrombosis in the Chinese population. One of the contributions to the surface potential in charged phospholipid monolayers at air-water interfaces is the double layer potential. Forty-one of the fatalities occurred around the home with only two being over the age of six years.

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The visual functions, before and after surgery, of 19 children with bilateral congenital cataract are evaluated. However, recent studies have found that overweight and obesity by themselves may be protective in some contexts, such as hospitalization in an intensive care unit (ICU). Previous work has found a high prevalence of pulmonary arterial hypertension in HIV-infected persons, but establishment of a causal relationship has been limited by the lack of well characterized contemporaneous HIV-uninfected comparator groups.

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Therefore, these factors are recommended in the first place for inclusion in a correction model. Chromatographic separation of catecholamines on a weakly acidic ion-exchange resin. Best-corrected visual acuity (BCVA) and central retinal thickness (CRT) were examined at each visit.

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Comparing with the commonly used low-level feature descriptors in previous works, LNND descriptor has two major advantages. In cervical smears and placental fragments the presence of HPV DNA and typing of HPV using the PCR method has been done. Evaluation of quality of life and anxiety and depression levels in patients receiving chemotherapy for colorectal cancer: impact of patient education before treatment initiation.

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A PubMed search was performed to select the articles containing information about the critical events (recurrence/death), time to events, and treatment characteristics (extent of resection with or without RT) in the patients with spinal myxopapillary ependymomas. Inbred strains of mice display different susceptibilities to experimental induction of reactive amyloidosis. Preparation of raspberry-like polymer particles by a heterocoagulation technique utilizing hydrogen bonding interactions between steric stabilizers. In this study, we evaluated the prognosis of this combined technique.

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The integrated system is effective when there is a need for loading measurements in specific plantar foot subareas. TA3 triggers liver injury through inducing ROS generation and suppressing the expression of BA transporters. However, to date, only two-hybrid methodology has been used in a systematic fashion to characterize viral-host protein-protein interactions, although a deluge of data exists in databases that manually curate from the literature individual host-pathogen PPIs.

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We analyzed 5 years of claims data from a large private insurer in Idaho to compare frequency by orthopedic surgeon owners and nonowners of surgical procedures that could be performed in either ambulatory surgery centers or hospital outpatient surgery departments. For tumor excision, a recently described modification of the traditional transsphenoidal approach was used. No studies have been found associating TSC with an increased risk of oral cancer, though it has been shown that the over-expression of TSC2 could exert an antitumor effect.

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A brief description of current procedures for the Chlamydia microimmunofluorescence (MIF) test is presented. Comparison of four different methods for the recovery of dotriacontane-16,17-14C from small animal respiratory tissue.

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Limbic epilepsy refers to a condition that consists of epileptic seizures that originate in or preferentially involve the limbic system. The integron from one isolate includes a large transposon-like structure containing four IS26 and the strAB, sul2, bla(TEM), and aphA1 genes conferring resistance to streptomycin, sulphonamides, ampicillin, kanamycin, and neomycin, respectively. Future cohort studies should preferably use infertile women as the reference group, rely on IVF-registered valid exposure data, adjust for a variety of meaningful confounders and adopt relatively longer follow-up periods before sound conclusions are drawn.

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The teeth in the first 4 groups were restored with cast (A1.3 and A1.6) and fiber (B1.3 and B1.6) posts of 1.3 and 1.7 mm diameters. Protocol for an evaluative study of the protective effect of isolation systems and decontamination in patients with high susceptibility to infection.

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The radial artery is routinely used as a graft for surgical arterial myocardial revascularization. Despite some general guidance as provided in the previous discussions, a number of ongoing questions remain. Although sequelae include chronotropic incompetence and neoaortic, pulmonary, and coronary artery complications, most patients maintain normal systolic function and exercise capacity.

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Rupture of the flexor digitorum superficialis at the musculotendinous junction due to a forearm fracture: a case report. These results demonstrate that the expression of glial NGF and BDNF may play a key role for helping survival and maintenance of pyramidal neurons and neuronal functions in the hippocampal CA1 sector during aging processes. Noteworthy is also the fact, that regardless of the selected detection method, sample preparation still remains the major bottleneck. However, a secondary evaluation of the anterior spine is essential to determining if an anterior graft remains needed. Emergency medical support system for extravehicular activity training held at weightless environment test building (WETS) of the Japan Aerospace Exploration Agency (JAXA) : future prospects and a look back over the past decade.

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Multidimensional attosecond resonant X-ray spectroscopy of molecules: lessons from the optical regime. In the ipsilateral digastric reflex discharge, there were an early phase induced by stimulus exciting Aalpha fibers and a late phase appearing when Adelta fibers were also stimulated. Toxin-specific ultrastructural alterations of the mouse liver after burn injuries and the possibility of a specific antitoxic therapy.

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Radiographic evaluation led to the discovery of an embedded foreign body requiring surgical removal. The Oxford hip score was found to be a useful precursor to the semi-structured interviews. Data from 113 residents, 137 caregivers, and 10 administrative personnel revealed that caregivers see themselves as the predominant decision makers. The average lengths obtained are muliples of about 10.4 bases, significantly different from the value of 10 previously reported.

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Our first hypothesis is that there are several pathways to the development of acute atherosis, which converge at the point of excessive decidual inflammation in the final common pathway. Prevention of allopregnanolone synthesis by the 5alpha-reductase inhibitor finasteride also prevented the changes in both GABA(A) receptor gene expression and receptor function elicited by progesterone treatment and withdrawal. Contribution to the study of the origin of tumoral cilioepithelial cells in ascites during malignant and benign neoplasms of the ovary The PAI-1 genotype distribution was similar in patients and controls.

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Shigella flexneri is a facultative intracellular pathogen that invades and disrupts the colonic epithelium. A case of Ph-positive chronic myelogenous leukemia in blastic crisis was studied extensively by means of cytogenetic techniques.

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The influences of the distance between both applicators were also investigated. Focal mesangial proliferative glomerulonephritis in the rat caused by Habu snake venom: the role of platelets. The levels of expression and location of axin, beta-catenin and TCF-4 before and after transfection were detected using immunofluorescence. 73.7 Tb/s (96 x 3 x 256-Gb/s) mode-division-multiplexed DP-16QAM transmission with inline MM-EDFA. However, direct stereotactic injection of recombinant adenoviral vectors into the pituitary achieved a high level of transgene expression.

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The purpose of this review is to bring together all the reported pulmonary manifestations of leptospirosis and the recent trends in the management. The natural-therapeutic resources of the health resort zone of Lake Sevan Socioeconomic factors and health insurance were important independent predictors of having a usual source of health care for men but had little effect among women. The common statement that supraspinatus initiates abduction is therefore, misleading. Nasal delivery systems and their effect on deposition and absorption.

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This reveals a characteristic unique to colloidal quantum dots that will promote the use of these versatile materials in challenging quantum technological applications. Survival and allotransplantation of cultured human parathyroids. Two pediatric emergency departments in the National Capital Region. Overall, a trend towards fewer stress lesions was found in the pirenzepine protected group. The disease involved two sites and remained active for seven months.

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Hepatocellular carcinoma (HCC) has one of the worst prognoses for survival as it is poorly responsive to both conventional chemotherapy and mechanism-directed therapy. Subjective data gathered included a daily patient diary and pre- and poststudy patient satisfaction measurements. The precipitation (free chitosan) in the solution was separated by centrifuging for about 10 min (4000 r/min). Prostaglandin F2 alpha output by human endometrium under superfusion and organ culture conditions.

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Changes in ovarian function in premenopausal women with breast cancer undergoing adjuvant TC (docetaxel and cyclophosphamide) chemotherapy during a ketoconazole dose dog brief period of amenorrhea around the last chemotherapy cycle. Significant regression of atherosclerosis was seen with rosuvastatin 40 mg/day in patients with established coronary heart disease (CHD) in the ASTEROID trial, supporting the use of intensive lipid lowering in secondary prevention patients (although it should be noted that it has not yet been established that atherosclerotic regression translates into improved cardiovascular outcomes).

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The influence of in vitro fitness defects on pneumococcal ability to colonize and to cause invasive disease. The combined influence of these factors appears to cause variable histologic appearances and rates of tissue deposition. Transient injuries on sensory fibers can produce either positive or negative symptoms of neuropathic pain, and the different extent of sensory fiber loss after nateglinide missed dose of celexa different degrees of injuries might account for the varied resulting symptoms of neuropathic pain. However, its role in embryonic stem cells (ESCs) remains unknown. Hexokinase deficiency in erythrocytes: a new variant in 5 members of a Finnish family.

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