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Ezetimibe/simvastatin was more effective than atorvastatin in lowering LDL-C at each dose comparison and provided greater increases in HDL-C at the 40- and 80-mg statin dose. Ezetimibe was administered to 20 patients with hypercholesterolemia (group E), and 20 age- and sex-matched patients with hypercholesterolemia were followed as controls (group C).

Other names for this medication:
Ezetimibe, Zetia, Ezedoc, Ezetimiba, Ezetrol, Zient,

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Ezetimibe is used together with lifestyle changes (diet, weight-loss, exercise) to reduce the amount of cholesterol (a fat-like substance) and other fatty substances in the blood. It may be used alone or in combination with an HMG-CoA reductase inhibitor (statin). Ezetimibe is in a class of medications called cholesterol-lowering medications. It works by preventing the absorption of cholesterol in the intestine.

Buildup of cholesterol and fats along the walls of the blood vessels (a process known as atherosclerosis) decreases blood flow, which decreases the oxygen supply to the heart, brain, and other parts of the body. Lowering blood levels of cholesterol and fats may help reduce this buildup and may decrease your chances of developing heart conditions such as angina (chest pain), strokes, and heart attacks. Results of a clinical study that compared people who took ezetimibe and simvastatin with people who took simvastatin alone found that although the group of people taking ezetimibe and simvastatin had lower amounts of cholesterol in the blood, there was no difference between the two groups in the amount of cholesterol and fat buildup on the insides of the blood vessels in the neck. It is not currently understood why the additional lowering of cholesterol levels in the blood did not lead to a greater decrease in cholesterol and fat buildup along the walls of the blood vessels in people taking ezetimibe and simvastatin. Further studies are underway to compare treatment with ezetimibe and simvastatin to treatment with simvastatin alone to see if there is a difference in the risk of developing heart disease. Talk to your doctor if you have questions about the risks and benefits of treating increased amounts of cholesterol in your blood with ezetimibe and other medications.

In addition to taking a cholesterol-lowering medication, making certain changes in your daily habits can also lower your blood cholesterol levels. You should eat a diet that is low in saturated fat and cholesterol (see SPECIAL DIETARY); exercise 30 minutes on most, if not all, days; and lose weight if you are overweight.

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Exogenously added CLIP rapidly localized into the subcellular compartment of antigen-presenting cells where MHC class II molecules are present. Future studies to assess the ability of these biomarkers to quantify and monitor MPS skeletal disease in response to therapy are needed. Functional morbidity following latissimus dorsi flap breast reconstruction. The intent of this tutorial is to briefly introduce key ABA principles, provide examples of ABA-based interventions used within schools, and identify strategies for successful collaboration between behavior analysts and SLPs. Analysis of interference under various temperature restrictions in Sphaerocarpos.

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The sources of ROS, however, are still controversial as well as their major molecular targets. Coronary heart surgery in women: the risk factors and short-term results In such cases it has a distinct tendency to mimic a C2-arch fracture. In addition, statins are beneficial by preserving endothelial function, possibly through inactivation of the RhoA/Rho-kinase pathway.

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Empyema is a potential complication of community acquired pneumonia but factors predicting this complication are lacking. The effects of yohimbine and urapidil hydrochloride on cell proliferation were assessed by 3-(4,5-dimethylthiasol-2-yl)-2,4,-diphenyltetrazolium bromide (MTT) assay. Tumor necrosis factor alpha drugs in rheumatoid arthritis: systematic review and metaanalysis of efficacy and safety. Activities of various enzymes of the pentosephosphate cycle during experimental arteriosclerosis induced in various ways Although some patients may receive durable remission of melanoma following explantation of the allograft and withdrawal of immunosuppression, donor transmission of melanoma is fatal in most patients.

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Any variation in buccal surface morphology of the deciduous first molars was recorded photographically or by replicating in dental stone. Clinical follow-up for 38 months showed a progressive and sustained improvement of dystonia with unchanged electrical settings throughout the observation period. The primary objective of the study was to quantify the effect of genetic improvement using the Irish total merit index (Economic Breeding Index) on dry matter intake and feed efficiency across lactation and to quantify the variation in performance among alternative definitions of feed efficiency. There were no significant complications in studying these children under general anesthesia. In this work chlorophyll fluorescence emission and photochemical parameters in plants of Populus x euramericana clone I-214 were investigated by the portable Imaging PAM fluorometer at different days after soil treatment with zinc.

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Three cell lines (differently resistant to chemotherapy) were used in this study: Bcap-37 (IC(50): 289.77 microg/ml), T47D (IC(50): 134.16 microg/ml) and ZR-75-30 (IC(50): 4.20 microg/ml). The stress, social support, and burnout of critical care nurses: the results of research. Finally, this study sheds light on a novel mechanism of immune homeostasis through synchronous regulation of co-inhibitory molecules on T cells, highly relevant to heterologous prime boost approaches involving DNA vaccines as priming agents.

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However, it is uncertain whether this change is specific to NMO, or is also seen in MS and other neurological diseases. In order to understand the molecular epidemiology of the disease and to establish the origin of the virus in the country, the study presented here intended to evaluate the presence of PCV2-associated systemic infection in piglets from different geographical regions over a period of 9-years (2002-2010). Endarterectomy results in satisfactory restoration of distal arterial flow. Social hygienic and epidemiological observations in multiple sclerosis Performance and return-to-sport after ACL reconstruction in NFL quarterbacks.

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Effects of acute and chronic ethanol administration on isoflurane requirement in mice. Evidence of an intracellular proteinase of Penicillium chrysogenum. An important finding in this model of basophilopoiesis was the marked early expansion of blasts which were not distinguishable morphologically from a proliferation of large lymphoid cells and lymphoblasts. During orthodontic-surgical treatment, orthodontics must facilitate the surgery, and vice-versa. When mice were kept continuously intoxicated by inhalation of ethanol, physical dependence developed progressively, reaching its maximum in about 2 weeks.

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Diversity of proteases in the keratinolytic larvae of the webbing clothes moth, Tineola bisselliella. Genome-wide subcellular localization of putative outer membrane and extracellular proteins in Leptospira interrogans serovar Lai genome using bioinformatics approaches.

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Patient underwent surgical operation and a lumbar abscess has been found containing a foreign body (toothpick). Because of the formation of a chain-like or lattice-like structure of dispersed nanorods along the electric field, the fluid shows a hyperbolic equifrequency contour characteristic and, as a result, all-angle broadband optical negative refraction for transverse magnetic wave propagation can be realized. Here, we show in a proof-of-concept that computational approaches are able to retain functional information about microbial communities assessed through 16S rDNA (meta)barcoding by referring to reference genomes.

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Mouse hepatitis virus replicase proteins associate with two distinct populations of intracellular membranes. However, tanapoxvirus (TPV), a member of the genus Yatapoxvirus, still remains largely unexplored, as the only known hosts for this virus are humans and monkeys. A solid-state (17)O NMR study of L-tyrosine in different ionization states: implications for probing tyrosine side chains in proteins. Furthermore, we considered new strategies for increasing vaccination coverage.

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Anatomical patterns and correlated MRI findings of non-perinatal hypoxic-ischaemic encephalopathy. These findings indicate that in organ culture there is a low basic turnover of human intestinal membrane glycoproteins which co-migrate on gels with known glycosidase enzymic activities. Anatomic data on the lines of action and moment arms for the intrinsic laryngeal muscles are also lacking. The isolation and analysis of a polypeptide from hamster zygotes during the early stages (2-cell) of pregnancy is reported.

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Preconference and postconference questionnaires measured knowledge, research-related confidence, beliefs about institutional support for emergency medical services for children (EMSC) research, and intentions to engage in 7 specific behaviors relating to scholarship, leadership, and partnership. The extracellular compartments of most biological tissues are significantly less well protected against oxidative damage than intracellular sites and there is considerable evidence for such compartments being subject to a greater oxidative stress and an altered redox balance.

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The liver functions could be held at nearly physiological values over a period of 10 hr. Hypothermia during treatment with alpha methyl dopa (a case report).

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Here we report that bacteriophage phi29 DNA packaging motor exercises a one-way traffic property for dsDNA translocation from N-terminal entrance to C-terminal exit with a valve mechanism in DNA packaging, as demonstrated by voltage ramping, electrode polarity switching, and sedimentation force assessment. The results demonstrate the ability of ET-1 to induce an inflammatory response in human vascular SMC. Treatment with shunts with low working pressure resulted in an increased incidence of SDH (iSDH).

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strain FS-1 exhibits inducible resistance to chloramphenicol (Cmr) and tetracycline (Tcr). Critical analysis of the determination of the time of death based on biochemical studies of cerebrospinal fluid and serum

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Integrating theory and method in the study of positive youth development: the sample case of gender-specificity and longitudinal stability of the dimensions of intention self-regulation (selection, optimization, and compensation). Diagnostic accuracy of magnetic resonance imaging versus clinical staging in cervical cancer. Separation of LATS from sera containing both LATS and TSH by dextran-coated charcoal.

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Brain metastases are the main determining factor in the failure of patients with locally advanced non-small cell lung cancer (LA-NSCLC) by multimodality treatments. The largest group of violent offenders with schizophrenia show no antisocial behaviour prior to the onset of the illness and then repeatedly engage in aggressive behaviour towards others. Under continuous electrocardiogram monitoring, IV lidocaine (5 mg kg(-1) in 100 mL saline) was administered over 30 minutes to 7 non-insulin-dependent diabetic patients suffering from neuropathic pain who reported increased pain within the preceding 6 months. Applying PCMM model is caused increasing staff and manager attention in identifying the weaknesses in the current activities and practices, so it will result in improvement and developing processes. Endodontically treated teeth: characteristics and considerations to restore them.

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Finally, we describe the first transcriptional profile of the C. c-erbB-2 is of independent prognostic relevance in gastric cancer and is associated with the expression of tumor-associated protease systems. A case of osteogenic osteosarcoma of temporoparietal bone that developed 56 months after irradiation for a cerebellar astrocytoma in a 10-year-old child is reported and the pertinent literature is briefly reviewed. In patients with un-embrional RMS, large size of lesion, cervical origin and extent of disease, survival rates was decreased. Effect of various restricted dietary regimens on the growth, health and longevity of albino rats.

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Patients with antibodies to intracellular neuronal antigens (onconeuronal antibodies: Hu, Ma2, amphiphysin, CV2/CRMP5) almost invariably have an underlying neoplasm (lung, testis, breast, etc.), often require aggressive combined antineoplastic and immunomodulatory treatment and their prognosis is usually poor. The flap was partially de-epithelialized to favor tissue cicatrix formation where the sutures are placed and avoid fistula formation. Less benefit from warfarin in diabetics after myocardial infarction? Postmortem and ex vivo carbon monoxide ventilation reduces injury in rat lungs transplanted from non-heart-beating donors. Evidence for transcortical reflex pathways in the lower limb of man.

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Potassium repletion with potassium chloride and/or spironolactone in patients with aldosterone-producing adenomas decreased the 180HB:PAC ratio by decreasing 180HB and increasing PAC. We summarize the literature about the evaluation of liver function.

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Our data show that BRAF inhibitor-mediated activation of EGFR-SFK-STAT3 signaling can mediate resistance in patients with BRAF-mutant melanoma. Therefore, our objective was to investigate the effect of pretreatment with the antihistamine fexofenadine on the incidence of allergic side-effects during ultrarush immunotherapy with bee venom. Tristetraprolin (TTP/zinc finger protein 36) family proteins have antiinflammatory effects by destabilizing proinflammatory mRNA. Fungi in the genus Lecanicillium (formerly classified as the single species Verticillium lecanii) are important pathogens of insects and some have been developed as commercial biopesticides.

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We reconsider the method of Ott and Falk (1982) for the analysis of genetic linkage and of epistasis in the presence of phenotypic association. Influence of liquoid on electrophoretic mobility and some thrombocytic properties. B-cell receptor signaling in chronic lymphocytic leukemia leans on Lyn.

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SWI/SNF subunits contribute to lncRNA-mediated transcriptional silencing. A ureteral stricture is a rather rare urological event defined as a narrowing of the ureter causing a functional obstruction and renal failure, if left untreated. The increase of caspase-3 activity, decrease of Bcl-XL expression, phosphorylation of p38 mitogen-activated protein kinase (MAPK) and accumulation of intracellular reactive oxygen species (ROS) were also seen in CoCl2-treated PC12 cells. Findings may inform and enhance strategies intended to engage young people with community-based recovery-focused 12-step MHOs and ultimately improve recovery outcomes.

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Millingtonia hortensis Linn is an abundant resource of flavonoids, which might be beneficial in protecting liver tissue from injury. Significant negative correlations of the mood and feelings questionnaire scores with mean ReHo values in the medial frontal gyrus and the right middle frontal gyrus in PBD-depression patients were observed. The effects of RES on activation of unfolded protein responses (UPR) were evaluated using Western blotting, semi-quantitative and real-time RT-PCR.

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Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and caduet generico de cialis phosphatidylinositol 3-kinase signaling in cancer cells. Metabolic effects of bretylium and phentolamine in euthyroid and thyrotoxic rats. Therefore, the aquatic organisms living in estuaries have to face highly variable environmental conditions. Messenger RNA properties of primary cultures of thyroid cells isolated from normal thyroid tissue and from patients with various thyroid diseases. The combination of mDRA-6 and nimesulide exhibits synergistic lethal effect on SMMC-7721 cells.

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The aim of this study was to investigate whether adding delayed phase imaging can improve diagnostic ability of (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET) in evaluating solitary pulmonary nodules (SPNs). Metabolic depression and increased reactive oxygen species production by isolated mitochondria at moderately lower temperatures. This tamsulosin hydrochloride erectile dysfunction study compared the amount of adhesion of plaque components (bacterial cells and glucans) on porcelain disks with various degrees of surface roughness to assess the effects of surface roughness on the amount of plaque accumulation.

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It was demonstrated that the majority of induced genes are downregulated in wild-type and atg5(-/-) MEF cells, indicating that autophagy exhibits a trend toward downregulation after treatment with PEI. Furthermore, this study demonstrated that aversive learning is elicited by elaborate actions of NMDA receptors, adenosine A2a receptors, and endocannabinoid CB1 receptors, which serve as key neurotransmitter receptors in inducing long-term potentiation in the indirect pathway. A biomathematical model of the human bony orbit, depicted as a thin-walled truncated conical shell, was devised. Histidine-rich glycoprotein inhibits the antithrombin activity generic cialis contrareembolso of heparin cofactor II in the presence of heparin or dermatan sulfate.

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